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T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

Targeted delivery of compounds to particular cell subsets can enhance therapeutic index by concentrating their action on the cells of interest. Because attempts to target tumors directly have yielded limited benefit, we instead target endogenous immune cell subsets in the circulation that can migrat...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Schmid, Daniela, Park, Chun Gwon, Hartl, Christina A., Subedi, Nikita, Cartwright, Adam N., Puerto, Regina Bou, Zheng, Yiran, Maiarana, James, Freeman, Gordon J., Wucherpfennig, Kai W., Irvine, Darrell J., Goldberg, Michael S.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700944/
https://ncbi.nlm.nih.gov/pubmed/29170511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01830-8
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