Comparison of the effect of the aerobic glycolysis inhibitor dichloroacetate and of the Krebs cycle inhibitor LW6 on cellular and humoral alloimmunity

Cell metabolism is altered during T-cell and B-cell activation and differentiation. Clarifying the exact metabolic shifts may lead to the development of new immunosuppressive medications. In this study, the effect of the aerobic glycolysis inhibitor dichloroacetate (DCA) and of the Krebs cycle enzym...

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Vydáno v:Biomed Rep
Hlavní autoři: Eleftheriadis, Theodoros, Pissas, Georgios, Mavropoulos, Athanasios, Liakopoulos, Vassilios, Stefanidis, Ioannis
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700391/
https://ncbi.nlm.nih.gov/pubmed/29181155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.980
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