Comparison of the effect of the aerobic glycolysis inhibitor dichloroacetate and of the Krebs cycle inhibitor LW6 on cellular and humoral alloimmunity

Cell metabolism is altered during T-cell and B-cell activation and differentiation. Clarifying the exact metabolic shifts may lead to the development of new immunosuppressive medications. In this study, the effect of the aerobic glycolysis inhibitor dichloroacetate (DCA) and of the Krebs cycle enzym...

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Detalhes bibliográficos
Publicado no:Biomed Rep
Main Authors: Eleftheriadis, Theodoros, Pissas, Georgios, Mavropoulos, Athanasios, Liakopoulos, Vassilios, Stefanidis, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700391/
https://ncbi.nlm.nih.gov/pubmed/29181155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.980
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