Pharmacokinetic Interactions between Simeprevir and Ledipasvir in Treatment-Naive Hepatitis C Virus Genotype 1-Infected Patients without Cirrhosis Treated with a Simeprevir-Sofosbuvir-Ledipasvir Regimen

Interactions between simeprevir (hepatitis C virus [HCV] NS3/4A protease inhibitor) and ledipasvir (HCV NS5A replication complex inhibitor) were investigated in treatment-naive HCV genotype 1-infected patients without cirrhosis, treated with simeprevir-sofosbuvir-ledipasvir in a two-panel, phase 2,...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bourgeois, Stefan, Horsmans, Yves, Nevens, Frederik, van Vlierberghe, Hans, Moreno, Christophe, Beumont, Maria, Vijgen, Leen, van Eygen, Veerle, Luo, Donghan, Hillewaert, Vera, Van Remoortere, Pieter, van de Logt, Jolanda, Ouwerkerk-Mahadevan, Sivi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700296/
https://ncbi.nlm.nih.gov/pubmed/28971875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01217-17
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