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Drug–Drug Interactions with the NS3/4A Protease Inhibitor Simeprevir
Simeprevir is an NS3/4A protease inhibitor approved for the treatment of hepatitis C infection, as a component of combination therapy. Simeprevir is metabolized by the cytochrome P450 (CYP) system, primarily CYP3A, and is a substrate for several drug transporters, including the organic anion transpo...
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| Publicado no: | Clin Pharmacokinet |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756048/ https://ncbi.nlm.nih.gov/pubmed/26353895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0314-y |
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