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MafB is a critical regulator of complement component C1q

The transcription factor MafB is expressed by monocytes and macrophages. Efferocytosis (apoptotic cell uptake) by macrophages is important for inhibiting the development of autoimmune diseases, and is greatly reduced in Mafb-deficient macrophages. Here, we show the expression of the first protein in...

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Vydáno v:Nat Commun
Hlavní autoři: Tran, Mai Thi Nhu, Hamada, Michito, Jeon, Hyojung, Shiraishi, Risako, Asano, Keigo, Hattori, Motochika, Nakamura, Megumi, Imamura, Yuki, Tsunakawa, Yuki, Fujii, Risa, Usui, Toshiaki, Kulathunga, Kaushalya, Andrea, Christina-Sylvia, Koshida, Ryusuke, Kamei, Risa, Matsunaga, Yurina, Kobayashi, Makoto, Oishi, Hisashi, Kudo, Takashi, Takahashi, Satoru
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700178/
https://ncbi.nlm.nih.gov/pubmed/29167450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01711-0
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