Recurring Amplification at 11q22.1-q22.2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC

A key feature in the pathogenesis of OSCC is genetic instability, which results in altered expression of genes located in amplified/deleted chromosomal regions. In a previous study we have shown that the amplification of the 11q22.1-q22.2 region, encoding cIAP1 and cIAP2, is associated with lymph no...

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Publicado no:Sci Rep
Main Authors: Bhosale, Priyanka G., Pandey, Manishkumar, Cristea, Simona, Shah, Mickey, Patil, Asawari, Beerenwinkel, Niko, Schäffer, Alejandro A., Mahimkar, Manoj B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700126/
https://ncbi.nlm.nih.gov/pubmed/29167558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16247-y
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