Cargando...

Synergistic Enhancement of Topotecan-Induced Cell Death by Ascorbic Acid in Human Breast MCF-7 Tumor Cells

Topotecan, a derivative of camptothecin, is an important anticancer drug for the treatment of various human cancers in the clinic. While the principal mechanism of tumor cell killing by topotecan is due to its interactions with topoisomerase I, other mechanisms, e.g., oxidative stress induced by rea...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Free Radic Biol Med
Autores principales: Sinha, Birandra K., van ‘t Erve, Thomas J., Kumar, Ashutosh, Bortner, Carl D., Motten, Ann G., Mason, Ronald P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699936/
https://ncbi.nlm.nih.gov/pubmed/29079526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.10.377
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!