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Bacterial cupredoxin azurin hijacks cellular signaling networks: Protein–protein interactions and cancer therapy

Azurin secreted by Pseudomonas aeruginosa is an anticancer bacteriocin, which preferentially enters human cancer cells and induces apoptosis or growth inhibition. It turns out that azurin is a multi‐target anticancer agent interfering in the p53 signaling pathway and the non‐receptor tyrosine kinase...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Gao, Meng, Zhou, Jingjing, Su, Zhengding, Huang, Yongqi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699490/
https://ncbi.nlm.nih.gov/pubmed/28960574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3310
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