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Basic requirements for a metal-binding site in a protein: The influence of loop shortening on the cupredoxin azurin

The main active-site loop of the copper-binding protein azurin (a cupredoxin) has been shortened from C(112)TFPGH(117)SALM(121) to C(112)TPH(115)PFM(118) (the native loop from the cupredoxin amicyanin) and also to C(112)TPH(115)PM(117). The Cu(II) site structure is almost unaffected by shortening, a...

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Bibliografiske detaljer
Main Authors: Li, Chan, Yanagisawa, Sachiko, Martins, Berta M., Messerschmidt, Albrecht, Banfield, Mark J., Dennison, Christopher
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464330/
https://ncbi.nlm.nih.gov/pubmed/16651527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600774103
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