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Biomimetic Platinum-Promoted Polyene Polycyclizations – Influence of Alkene Substitution and Pre-Cyclization Conformations

Results of kinetic experiments and quantum chemical computations on a series of platinum-promoted polycyclization reactions are described. Analysis of these results reveal a reactivity model that reaches beyond the energetics of the cascade itself, incorporating an ensemble of pre-cyclization confor...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: McCulley, Christina, Geier, Michael J., Hudson, Brandi M., Gagné, Michel R., Tantillo, Dean J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699452/
https://ncbi.nlm.nih.gov/pubmed/28719198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b05381
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