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Interleukin 17 Selectively Predicts Better Outcomes with Bupropion-SSRI Combination: Novel T Cell Biomarker for Antidepressant Medication Selection

BACKGROUND: Interleukin 17 (IL-17) is produced by highly inflammatory Th17 cells and has been implicated in pathophysiology of depression. IL-17 putatively disrupts the blood brain barrier and affects dopamine synthesis whereas dopamine has been shown to decrease Th17 cell-mediated immune response....

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Détails bibliographiques
Publié dans:Brain Behav Immun
Auteurs principaux: Jha, Manish K., Minhajuddin, Abu, Gadad, Bharathi, Greer, Tracy L., Mayes, Taryn L., Trivedi, Madhukar H.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699207/
https://ncbi.nlm.nih.gov/pubmed/28698115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.07.005
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