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Higher S100B Levels Predict Persistently Elevated Anhedonia with Escitalopram Monotherapy Versus Antidepressant Combinations: Findings from CO-MED Trial

Background: Elevated S100 calcium binding protein B (S100B) levels in systemic circulation may induce neuroinflammation and reflect greater blood–brain barrier (BBB) dysfunction. Neuroinflammation in patients with major depressive disorder (MDD), in turn, may reduce likelihood of improvement with se...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Jha, Manish K., Minhajuddin, Abu, Gadad, Bharathi S., Chin Fatt, Cherise, Trivedi, Madhukar H.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958482/
https://ncbi.nlm.nih.gov/pubmed/31861074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12040184
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