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Flexible semiparametric joint modeling: an application to estimate individual lung function decline and risk of pulmonary exacerbations in cystic fibrosis

BACKGROUND: Epidemiologic surveillance of lung function is key to clinical care of individuals with cystic fibrosis, but lung function decline is nonlinear and often impacted by acute respiratory events known as pulmonary exacerbations. Statistical models are needed to simultaneously estimate lung f...

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Publicado en:Emerg Themes Epidemiol
Autores principales: Li, Dan, Keogh, Ruth, Clancy, John P., Szczesniak, Rhonda D.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699130/
https://ncbi.nlm.nih.gov/pubmed/29201130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12982-017-0067-1
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