Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs

Pluripotent stem cell-derived human primordial germ cell-like cells (hPGCLCs) provide important opportunities to study primordial germ cells (PGCs). We robustly produced CD38(+) hPGCLCs [∼43% of FACS-sorted embryoid body (EB) cells] from primed-state induced pluripotent stem cells (iPSCs) after a 72...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Mitsunaga, Shino, Odajima, Junko, Yawata, Shiomi, Shioda, Keiko, Owa, Chie, Isselbacher, Kurt J., Hanna, Jacob H., Shioda, Toshi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699045/
https://ncbi.nlm.nih.gov/pubmed/29087313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707779114
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