Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism

[Image: see text] Many women consider botanical dietary supplements (BDSs) as safe alternatives to hormone therapy for menopausal symptoms. However, the effect of BDSs on breast cancer risk is largely unknown. In the estrogen chemical carcinogenesis pathway, P450 1B1 metabolizes estrogens to 4-hydro...

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Detaylı Bibliyografya
Yayımlandı:Chem Res Toxicol
Asıl Yazarlar: Dunlap, Tareisha L., Howell, Caitlin E., Mukand, Nita, Chen, Shao-Nong, Pauli, Guido F., Dietz, Birgit M., Bolton, Judy L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2017
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698877/
https://ncbi.nlm.nih.gov/pubmed/28985473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00237
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