A Simple and Broadly Applicable C−N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents

A C−N bond forming dearomatization protocol with broad scope is outlined. Specifically, bifunctional amino reagents are used for sequential nucleophilic and electrophilic C−N bond formations, with the latter effecting the key dearomatization step. Using this approach, γ‐arylated alcohols are convert...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Ma, Xiaofeng, Farndon, Joshua J., Young, Tom A., Fey, Natalie, Bower, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698738/
https://ncbi.nlm.nih.gov/pubmed/28925055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201708176
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