FXR controls CHOP expression in steatohepatitis

The farnesoid X receptor (FXR) and C/EBP homologous protein (CHOP) have critical functions in hepatic lipid metabolism. Here, we aimed to explore a potential relationship between FXR and CHOP. We fed wild‐type (WT) and FXR KO mice a MCD diet (model of steatohepatitis) and found that Chop mRNA expres...

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Bibliographic Details
Published in:FEBS Lett
Main Authors: Fuchs, Claudia D., Claudel, Thierry, Scharnagl, Hubert, Stojakovic, Tatjana, Trauner, Michael
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Research Letters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698708/
https://ncbi.nlm.nih.gov/pubmed/28895119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12845
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