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Population pharmacokinetics of oxcarbazepine and its monohydroxy derivative in epileptic children
AIMS: Oxcarbazepine is an antiepileptic drug with an activity mostly due to its monohydroxy derivative metabolite (MHD). A parent‐metabolite population pharmacokinetic model in children was developed to evaluate the consistency between the recommended paediatric doses and the reference range for tro...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698580/ https://ncbi.nlm.nih.gov/pubmed/28771787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13392 |
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