CD4(+) T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis

Cryptococcus neoformans is a major fungal pathogen that disseminates to the central nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune responses within this immune-privileged site. CD4(+) T cells have demonstrated roles in anticryptococcal defenses, but increas...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Neal, Lori M., Xing, Enze, Xu, Jintao, Kolbe, Jessica L., Osterholzer, John J., Segal, Benjamin M., Williamson, Peter R., Olszewski, Michal A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698549/
https://ncbi.nlm.nih.gov/pubmed/29162707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01415-17
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