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TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity
STAT3 is a pleiotropic transcription factor involved in homeostatic and host defense processes in the human body. It is activated by numerous cytokines and growth factors and generates a series of cellular effects. Of the STAT-mediated signal transduction pathways, STAT3 transcriptional control is b...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698428/ https://ncbi.nlm.nih.gov/pubmed/29162862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15912-6 |
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