The Sin3a repressor complex is a master regulator of STAT transcriptional activity

Tyrosine phosphorylation is a hallmark for activation of STAT proteins, but their transcriptional activity also depends on other secondary modifications. Type I IFNs can activate both the ISGF3 (STAT1:STAT2:IRF9) complex and STAT3, but with cell-specific, selective triggering of only the ISGF3 trans...

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Detalhes bibliográficos
Main Authors: Icardi, Laura, Mori, Raffaele, Gesellchen, Viola, Eyckerman, Sven, De Cauwer, Lode, Verhelst, Judith, Vercauteren, Koen, Saelens, Xavier, Meuleman, Philip, Leroux-Roels, Geert, De Bosscher, Karolien, Boutros, Michael, Tavernier, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409767/
https://ncbi.nlm.nih.gov/pubmed/22783022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206458109
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