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TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response

Adult neurogenesis persists in the rodent dentate gyrus and is stimulated by chronic treatment with conventional antidepressants through BDNF/TrkB signaling. Ketamine in low doses produces both rapid and sustained antidepressant effects in patients. Previous studies have shed light on post-transcrip...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ma, Zhenzhong, Zang, Tong, Birnbaum, Shari G., Wang, Zilai, Johnson, Jane E., Zhang, Chun-Li, Parada, Luis F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698402/
https://ncbi.nlm.nih.gov/pubmed/29162814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01709-8
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