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FUNCTIONAL SIGNIFICANCE OF C-TERMINAL MOBILE DOMAIN OF CARDIAC TROPONIN I
Ca(2+)-regulation of cardiac contractility is mediated through the troponin complex, which comprises three subunits: cTnC, cTnI, and cTnT. As intracellular [Ca(2+)] increases, cTnI reduces its binding interactions with actin to primarily interact with cTnC, thereby enabling contraction. A portion of...
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| Publicat a: | Arch Biochem Biophys |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698173/ https://ncbi.nlm.nih.gov/pubmed/28958680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2017.09.017 |
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