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The structure-energy landscape of NMDA Receptor gating

N-methyl-D-aspartate (NMDA) receptors are the main calcium-permeable excitatory receptors in the mammalian central nervous system. The NMDA receptor gating is complex, exhibiting multiple closed, open, and desensitized states; however, the central questions regarding the conformations and energetics...

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Publicat a:Nat Chem Biol
Autors principals: Dolino, Drew M., Chatterjee, Sudeshna, MacLean, David M., Flatebo, Charlotte, Bishop, Logan D.C., Shaikh, Sana A., Landes, Christy F., Jayaraman, Vasanthi
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698143/
https://ncbi.nlm.nih.gov/pubmed/28991238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2487
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