Molecular engineering and plant expression of an immunoglobulin heavy chain scaffold for delivery of a dengue vaccine candidate

In order to enhance vaccine uptake by the immune cells in vivo, molecular engineering approach was employed to construct a polymeric immunoglobulin G scaffold (PIGS) that incorporates multiple copies of an antigen and targets the Fc gamma receptors on antigen‐presenting cells. These self‐adjuvanting...

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Библиографические подробности
Опубликовано в: :Plant Biotechnol J
Главные авторы: Kim, Mi‐Young, Van Dolleweerd, Craig, Copland, Alastair, Paul, Matthew John, Hofmann, Sven, Webster, Gina R., Julik, Emily, Ceballos‐Olvera, Ivonne, Reyes‐del Valle, Jorge, Yang, Moon‐Sik, Jang, Yong‐Suk, Reljic, Rajko, Ma, Julian K.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698049/
https://ncbi.nlm.nih.gov/pubmed/28421694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12741
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