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Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak
Cells deficient in the pro-death Bcl-2 family members Bax and Bak are known to be resistant to apoptotic cell death, and previous we have shown that these two effectors are also needed for mitochondrial-dependent cellular necrosis (Karch et al., 2013). Here we show that mouse embryonic fibroblasts d...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5697932/ https://ncbi.nlm.nih.gov/pubmed/29148970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30543 |
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