TGF-β contamination of purified recombinant GDF15

Purified recombinant proteins for use in biomedical research are invaluable to investigate protein function. However, purity varies in protein batches made in mammalian expression systems, such as CHO-cells or HEK293-cells. This study points to caution while investigating effects of proteins related...

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Udgivet i:PLoS One
Main Authors: Olsen, Oddrun Elise, Skjærvik, Anette, Størdal, Berit Fladvad, Sundan, Anders, Holien, Toril
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697882/
https://ncbi.nlm.nih.gov/pubmed/29161287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187349
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