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TGF-β contamination of purified recombinant GDF15

Purified recombinant proteins for use in biomedical research are invaluable to investigate protein function. However, purity varies in protein batches made in mammalian expression systems, such as CHO-cells or HEK293-cells. This study points to caution while investigating effects of proteins related...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Olsen, Oddrun Elise, Skjærvik, Anette, Størdal, Berit Fladvad, Sundan, Anders, Holien, Toril
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697882/
https://ncbi.nlm.nih.gov/pubmed/29161287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187349
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