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Isoacceptor specific characterization of tRNA aminoacylation and misacylation in vivo

Amino acid misincorporation during protein synthesis occurs due to misacylation of tRNAs or defects in decoding at the ribosome. While misincorporation of amino acids has been observed in a variety of contexts, less work has been done to directly assess the extent to which specific tRNAs are misacyl...

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Vydáno v:Methods
Hlavní autoři: Mohler, Kyle, Mann, Rebecca, Ibba, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697713/
https://ncbi.nlm.nih.gov/pubmed/27639881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.09.003
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