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1,3‐Bis(aryloxy)propan‐2‐ols as potential antileishmanial agents

We describe herein the synthesis and antileishmanial activity of 1,3‐bis(aryloxy)propan‐2‐ols. Five compounds (2, 3, 13, 17, and 18) exhibited an effective antileishmanial activity against stationary promastigote forms of Leishmania amazonensis (IC (50) < 15.0 μm), and an influence of compound li...

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Publicat a:Chem Biol Drug Des
Autors principals: Lavorato, Stefânia N., Duarte, Mariana C., Lage, Daniela P., Tavares, Carlos A. P., Coelho, Eduardo A. F., Alves, Ricardo J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697679/
https://ncbi.nlm.nih.gov/pubmed/28590516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13024
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