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1,3‐Bis(aryloxy)propan‐2‐ols as potential antileishmanial agents

We describe herein the synthesis and antileishmanial activity of 1,3‐bis(aryloxy)propan‐2‐ols. Five compounds (2, 3, 13, 17, and 18) exhibited an effective antileishmanial activity against stationary promastigote forms of Leishmania amazonensis (IC (50) < 15.0 μm), and an influence of compound li...

詳細記述

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書誌詳細
出版年:Chem Biol Drug Des
主要な著者: Lavorato, Stefânia N., Duarte, Mariana C., Lage, Daniela P., Tavares, Carlos A. P., Coelho, Eduardo A. F., Alves, Ricardo J.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697679/
https://ncbi.nlm.nih.gov/pubmed/28590516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13024
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