Caffeine‐mediated BDNF release regulates long‐term synaptic plasticity through activation of IRS2 signaling

Caffeine has cognitive‐enhancing properties with effects on learning and memory, concentration, arousal and mood. These effects imply changes at circuital and synaptic level, but the mechanism by which caffeine modifies synaptic plasticity remains elusive. Here we report that caffeine, at concentrat...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: Lao‐Peregrín, Cristina, Ballesteros, Jesús Javier, Fernández, Miriam, Zamora‐Moratalla, Alfonsa, Saavedra, Ana, Gómez Lázaro, María, Pérez‐Navarro, Esther, Burks, Deborah, Martín, Eduardo D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Preclinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697621/
https://ncbi.nlm.nih.gov/pubmed/27457910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12433
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