Molecular Response to Imatinib and Its Correlation with mRNA Expression Levels of Imatinib Influx Transporter (OCT1) in Indian Chronic Myeloid Leukemia Patients

BACKGROUND AND OBJECTIVES: Imatinib mesylate is approved for the treatment of Chronic Myeloid Leukemia (CML). About 20% of patients with CML do not respond to treatment with Imatinib either initially or because of acquired resistance. In addition to mutated BCR-ABL1 kinase, the organic cation transp...

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Udgivet i:Asian Pac J Cancer Prev
Main Authors: Chhikara, S, Sazawal, S, Seth, T, Chaubey, R, Singh, K, Sharma, R, Mishra, P, Mahapatra, M, Saxena, R
Format: Artigo
Sprog:Inglês
Udgivet: West Asia Organization for Cancer Prevention 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697457/
https://ncbi.nlm.nih.gov/pubmed/28843219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2017.18.8.2043
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