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Molecular response to imatinib & its correlation with mRNA expression levels of imatinib influx & efflux transporters in patients with chronic myeloid leukaemia in chronic phase

BACKGROUND & OBJECTIVES: Imatinib is the standard first-line treatment for chronic myeloid leukaemia (CML) patients. About 20 to 30 per cent patients develop resistance to imatinib and fail imatinib treatment. One of the mechanisms proposed is varying expression levels of the drug transporters....

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Bibliografiske detaljer
Udgivet i:Indian J Med Res
Main Authors: Malhotra, Hemant, Sharma, Pratibha, Malhotra, Bharti, Bhargava, Shipra, Jasuja, Sandeep, Kumar, Madhu
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613438/
https://ncbi.nlm.nih.gov/pubmed/26354214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5916.164250
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