A carregar...
Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7
The metabolism of testosterone to 6β-hydroxytestosterone (6β-OH-T) is a commonly used assay to evaluate human CYP3A enzyme activities. However, previous reports have indicated that CYP3A7 also produces 2α-hydroxytestosterone (2α-OH-T) and that a 2α-OH-T/6β-OH-T ratio may be a unique endogenous bioma...
Na minha lista:
| Publicado no: | Drug Metab Dispos |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5697443/ https://ncbi.nlm.nih.gov/pubmed/28986474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.078055 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|