A validated antibody panel for the characterization of tau post-translational modifications

BACKGROUND: Tau is a microtubule-binding protein, which is subject to various post-translational modifications (PTMs) including phosphorylation, methylation, acetylation, glycosylation, nitration, sumoylation and truncation. Aberrant PTMs such as hyperphosphorylation result in tau aggregation and th...

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Bibliografski detalji
Izdano u:Mol Neurodegener
Glavni autori: Ercan, Ebru, Eid, Sameh, Weber, Christian, Kowalski, Alexandra, Bichmann, Maria, Behrendt, Annika, Matthes, Frank, Krauss, Sybille, Reinhardt, Peter, Fulle, Simone, Ehrnhoefer, Dagmar E.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697095/
https://ncbi.nlm.nih.gov/pubmed/29157277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0229-1
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