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Metabolic adaptation of two in silico mutants of Mycobacterium tuberculosis during infection

BACKGROUND: Up to date, Mycobacterium tuberculosis (Mtb) remains as the worst intracellular killer pathogen. To establish infection, inside the granuloma, Mtb reprograms its metabolism to support both growth and survival, keeping a balance between catabolism, anabolism and energy supply. Mtb knockou...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: López-Agudelo, Víctor A., Baena, Andres, Ramirez-Malule, Howard, Ochoa, Silvia, Barrera, Luis F., Ríos-Estepa, Rigoberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697012/
https://ncbi.nlm.nih.gov/pubmed/29157227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0496-z
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