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Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones

Optically active spirocyclic compounds play an important role in drug discovery, and new synthetic strategies for the efficient generation of spiro stereocenters are in much demand. Here we report a catalytic enantioselective cycloaddition using spirocyclic donor–acceptor cyclopropanes as a promisin...

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書目詳細資料
發表在:Nat Commun
Main Authors: Xu, Peng-Wei, Liu, Jia-Kuan, Shen, Lan, Cao, Zhong-Yan, Zhao, Xiao-Li, Yan, Jun, Zhou, Jian
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696380/
https://ncbi.nlm.nih.gov/pubmed/29158496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01451-1
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