Erythropoietin Attenuates Postoperative Cognitive Dysfunction by Shifting Macrophage Activation toward the M2 Phenotype

Postoperative cognitive dysfunction (POCD) may be driven by transference of the innate immune response to the brain after aseptic surgical damage. Macrophages are key mediators of innate immunity that can display a pro-inflammatory M1 phenotype or an anti-inflammatory M2 phenotype. Erythropoietin (E...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Pharmacol
Päätekijät: Lee, Jae Hoon, Kam, Eun Hee, Kim, So Yeon, Cheon, So Yeong, Kim, Eun Jung, Chung, Seungsoo, Jeong, Ji-Hyun, Koo, Bon-Nyeo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2017
Aiheet:
Pharmacology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696349/
https://ncbi.nlm.nih.gov/pubmed/29201007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00839
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