Blockade of Eosinophil-Induced Bronchial Epithelial-Mesenchymal Transition with a Geranyl Acetophenone in a Coculture Model

Epithelial-mesenchymal transition (EMT) is currently recognized as the main cellular event that contributes to airway remodeling. Eosinophils can induce EMT in airway epithelial cells via increased transforming growth factor (TGF)-β production. We assessed the effect of synthetic 2,4,6-trihydroxy-3-...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lee, Yu Z., Yap, Hui M., Shaari, Khozirah, Tham, Chau L., Sulaiman, Mohd R., Israf, Daud A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696322/
https://ncbi.nlm.nih.gov/pubmed/29201006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00837
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