2,4,6-Trihydroxy-3-geranyl acetophenone suppresses vascular leakage and leukocyte infiltration in lipopolysaccharide-induced endotoxemic mice

CONTEXT: Lipopolysaccharide (LPS) exacerbates systemic inflammatory responses and causes excessive fluid leakage. 2,4,6-Trihydroxy-3-geranyl acetophenone (tHGA) has been revealed to protect against LPS-induced vascular inflammation and endothelial hyperpermeability in vitro. OBJECTIVE: This study as...

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Detalhes bibliográficos
Publicado no:Pharm Biol
Main Authors: Chan, Yee Han, Musa, Nazmi Firdaus, Chong, Yi Joong, Saat, Siti Arfah, Hafiz, Faizul, Shaari, Khozirah, Israf, Daud Ahmad, Tham, Chau Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221152/
https://ncbi.nlm.nih.gov/pubmed/34155953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2021.1933083
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