Silibinin suppresses bladder cancer through down-regulation of actin cytoskeleton and PI3K/Akt signaling pathways

Silibinin is the major active constituent of silymarin, an extract of milk thistle seeds. Silibinin has been shown to have significant anti-cancer effects in a variety of malignancies. However, the molecular mechanisms of silibinin action in bladder cancer have not been studied extensively. In the p...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Imai-Sumida, Mitsuho, Chiyomaru, Takeshi, Majid, Shahana, Saini, Sharanjot, Nip, Hannah, Dahiya, Rajvir, Tanaka, Yuichiro, Yamamura, Soichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696161/
https://ncbi.nlm.nih.gov/pubmed/29190895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20734
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