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Metformin activates type I interferon signaling against HCV via activation of adenosine monophosphate-activated protein kinase
Activation of the type I interferon (IFN) signaling pathway is essential for the eradication of hepatitis C virus (HCV). Metformin can activate adenosine monophosphate-activated protein kinase (AMPK) to reduce insulin resistance. Cross talks between AMPK and IFN signaling remain unclear. To understa...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696152/ https://ncbi.nlm.nih.gov/pubmed/29190886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20248 |
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