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Adjusting for Covariates in Evaluating Markers for Selecting Treatment, With Application to Guiding Chemotherapy for Treating Estrogen-Receptor-Positive, Node-Positive Breast Cancer

In many clinical contexts, biomarkers that predict treatment efficacy are highly sought after. Such treatment selection or predictive biomarkers have the potential to identify subgroups most likely to benefit from the treatment, and may therefore be used to improve clinical outcomes and reduce medic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Contemp Clin Trials
Hauptverfasser: Janes, Holly, Brown, Marshall D., Crager, Michael R., Miller, Dave P., Barlow, William E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696084/
https://ncbi.nlm.nih.gov/pubmed/28818434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2017.08.004
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