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Adjusting for Covariates in Evaluating Markers for Selecting Treatment, With Application to Guiding Chemotherapy for Treating Estrogen-Receptor-Positive, Node-Positive Breast Cancer

In many clinical contexts, biomarkers that predict treatment efficacy are highly sought after. Such treatment selection or predictive biomarkers have the potential to identify subgroups most likely to benefit from the treatment, and may therefore be used to improve clinical outcomes and reduce medic...

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Bibliographic Details
Published in:Contemp Clin Trials
Main Authors: Janes, Holly, Brown, Marshall D., Crager, Michael R., Miller, Dave P., Barlow, William E.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696084/
https://ncbi.nlm.nih.gov/pubmed/28818434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2017.08.004
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