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Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis

Cancer genome sequencing has identified chromothripsis, a complex class of structural genomic rearrangements involving the apparent shattering of an individual chromosome into tens to hundreds of fragments. An initial error during mitosis, producing either chromosome missegregation into a micronucle...

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Publicat a:Trends Cell Biol
Autors principals: Ly, Peter, Cleveland, Don W.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696049/
https://ncbi.nlm.nih.gov/pubmed/28899600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2017.08.005
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