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Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis
Cancer genome sequencing has identified chromothripsis, a complex class of structural genomic rearrangements involving the apparent shattering of an individual chromosome into tens to hundreds of fragments. An initial error during mitosis, producing either chromosome missegregation into a micronucle...
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| Veröffentlicht in: | Trends Cell Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696049/ https://ncbi.nlm.nih.gov/pubmed/28899600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2017.08.005 |
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