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Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis

The aim of this study was to show how computational models can be used to increase our understanding of the role of microRNAs in osteoarthritis (OA) using miR-140 as an example. Bioinformatics analysis and experimental results from the literature were used to create and calibrate models of gene regu...

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Pubblicato in:PLoS One
Autori principali: Proctor, Carole J., Smith, Graham R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695613/
https://ncbi.nlm.nih.gov/pubmed/29095952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187568
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