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Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis

The aim of this study was to show how computational models can be used to increase our understanding of the role of microRNAs in osteoarthritis (OA) using miR-140 as an example. Bioinformatics analysis and experimental results from the literature were used to create and calibrate models of gene regu...

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Foilsithe in:PLoS One
Main Authors: Proctor, Carole J., Smith, Graham R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695613/
https://ncbi.nlm.nih.gov/pubmed/29095952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187568
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